1,2-Bis(2-iodoethoxy)ethane

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

1,2-双(2-碘乙氧基)乙烷是一种基于 PEG 的 PROTAC 连接剂。 1,2-双(2-碘乙氧基)乙烷可用于合成MT802和SJF620。

1,2-Bis(2-iodoethoxy)ethane is a PEG-based PROTAC linker. 1,2-Bis(2-iodoethoxy)ethane can be used in the synthesis of MT802 and SJF620. MT-802 and SJF620 are potent PROTAC BTK degraders with DC50s of 1 nM and 7.9 nM, respectively.(In Vitro):1,2-Bis(2-iodoethoxy)ethane is a PROTAC linker, which refers to the PEG composition. 1,2-Bis(2-iodoethoxy)ethane can be used in the synthesis of a series of PROTACs, such as MT802 and SJF620. PROTAC MT802 has a ligand specific for BTK, and a ligand specific to a E3 ligase cereblon (CRBN) connected by polyethylene glycol (PEG) linker 1,2-Bis(2-iodoethoxy)ethane.

1,2-Bis(2-iodoethoxy)ethane is a PROTAC linker, which refers to the PEG composition. 1,2-Bis(2-iodoethoxy)ethane can be used in the synthesis of a series of PROTACs, such as MT802 (HY-122562) and SJF620 (HY-133137). PROTAC MT802（HY-122562） has a ligand specific for BTK, and a ligand specific to a E3 ligase cereblon (CRBN) connected by polyethylene glycol (PEG) linker 1,2-Bis(2-iodoethoxy)ethane.

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Others

Other Targets

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36839-55-1

369.969

C6H12I2O2

>98% (HPLC)

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ICCOCCOCCI

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(-20℃)

With Ice Pack

≥ 2 years