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(Nle4)-α-MSH
CAS No. 64887-70-3
(Nle4)-α-MSH ( ——— )
产品货号. M40255 CAS No. 64887-70-3
(Nle4)-α-MSH 是一种黑素细胞刺激激素 α-MSH 的合成类似物。(Nle4)-α-MSH 能够使青蛙皮肤可逆变黑，并在热碱处理后表现出延长的活性。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 25MG | 获取报价 | 有现货 |
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| 50MG | 获取报价 | 有现货 |
|
| 100MG | 获取报价 | 有现货 |
|
生物学信息
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产品名称(Nle4)-α-MSH
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述(Nle4)-α-MSH 是一种黑素细胞刺激激素 α-MSH 的合成类似物。(Nle4)-α-MSH 能够使青蛙皮肤可逆变黑，并在热碱处理后表现出延长的活性。
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产品描述(Nle4)-α-MSH is a synthetic analogue of α-MSH, a melanocyte-stimulating hormone. (Nle4)-α-MSH reversibly darkens frog skins and also exhibits prolonged activity after heat-alkali treatment.
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体外实验———
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体内实验(Nle4)-α-MSH shows a better bioactivity than α-MSH in frog skin bioassay, activation of mouse melanoma adenylate cyclase, and stimulation of mouse melanoma cell tyrosinase activity.(Nle4)-α-MSH (0.1 nM; 0.5, 4, 8 h) stimulates tyrosinase activity in melanoma cells .(Nle4)-α-MSH (0.1 nM; 1-4 h) increases biological activity of melanotropins, indicatingdarkening response of frog skins.(Nle4)-α-MSH (0.1 μg) also activates mouse melanoma adenylate cyclase.
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同义词———
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通路Others
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靶点Other Targets
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受体tyrosinase; melanoma adenylate cyclase
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研究领域———
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适应症———
化学信息
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CAS Number64887-70-3
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分子量1646.85
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分子式C78H111N21O19
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纯度>98% (HPLC)
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溶解度———
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SMILES———
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化学全称———
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Sawyer TK, et al. 4-Norleucine, 7-D-phenylalanine-alpha-melanocyte-stimulating hormone: a highly potent alpha-melanotropin with ultralong biological activity. Proc Natl Acad Sci U S A. 1980 Oct;77(10):5754-8. ?
